publications
Pulled periodically from google scholar
2025
- Cancer Discov.Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repairCancer Discovery, 2025
- Nature Cell BioEnhancer activation from transposable elements in extrachromosomal DNANature cell biology, 2025
- NatureEngineered extrachromosomal oncogene amplifications promote tumorigenesisNature, 2025
- Nature Comms.Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3DNature Communications, 2025
- Nature Comms.Breakage fusion bridge cycles drive high oncogene number with moderate intratumoural heterogeneityNature communications, 2025
- medRxivOMKar: optical map based automated karyotyping of genomes to identify constitutional abnormalitiesmedRxiv, 2025
- Cancer Discov.Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune MicroenvironmentCancer discovery, 2025
- Nature Comms.Inhibition of human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancerNature Communications, 2025
- bioRxivEcDNA-borne PVT1 fusion stabilizes oncogenic mRNAsbioRxiv, 2025
- PLOS Comp. Bio.Analysis of targeted and whole genome sequencing of PacBio HiFi reads for a comprehensive genotyping of gene-proximal and phenotype-associated Variable Number Tandem RepeatsPLOS Computational Biology, 2025
- bioRxivOncogene Silencing via ecDNA MicronucleationbioRxiv, 2025
- Cancer Res.AmpliconSuite enables discovery of extrachromosomal DNA in tumor genomesCancer Research, 2025
- Cancer Res.Three-dimensional genome landscape of primary human cancersCancer Research, 2025
- Cancer Res.Engineered extrachromosomal oncogene amplifications promote tumorigenesisCancer Research, 2025
- RECOMBOMKar: Optical Map Based Automated Karyotyping of Genomes to Identify Constitutional DisordersIn International Conference on Research in Computational Molecular Biology, 2025
- Nature GeneticsThree-dimensional genome landscape of primary human cancersNature Genetics, 2025
- bioRxivAccurate Prediction of ecDNA in Interphase Cancer Cells using Deep Neural NetworksbioRxiv, 2025
- medRxivExtrachromosomal DNA associates with poor survival across a broad spectrum of childhood solid tumorsMedRxiv, 2025
- Neuro-Oncol. Peds.METB-07. Conservation of circular extrachromosomal DNA in xenograft mouse models derived from pediatric brain tumorsNeuro-Oncology Pediatrics, 2025
- Neuro-Oncol. Peds.METB-04. The genomic landscape of extrachromosomal amplifications across pediatric brain tumorsNeuro-Oncology Pediatrics, 2025
- bioRxivPreservation and Clonal Behavior of Extrachromosomal DNA in Patient-Derived Xenograft Models of Childhood CancersbioRxiv, 2025
- Genome Res.OMKar automates genome karyotyping using optical maps to identify constitutional abnormalitiesGenome Research, 2025
- bioRxivSPrUCE: Utilizing Ultraconserved Elements of DNA for Population-Level Genetic Diversity EstimationbioRxiv, 2025
- Adv. GeneticsRare Structural Variants Uncovered by Optical Genome Mapping in Multisystem Inflammatory Syndrome in Children (MIS-C)Advanced Genetics, 2025
- CellCorrection to: Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer (Cell,(2016), 166, 3,(755-765),(S0092867416306730), 10.1016/j. cell. 2016.05. 069)Cell, 2025
2024
- Genome Res.CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencingGenome Research, 2024
- Cancer Res.Chromosomal instability causes epigenetic aberrations in cancerCancer Research, 2024
- eLifeTranscriptional immune suppression and up-regulation of double-stranded DNA damage and repair repertoires in ecDNA-containing tumorsElife, 2024
- Cancer Res.The origins and clinical impact of extrachromosomal DNA across 39 cancersCancer Research, 2024
- bioRxivRampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancersbioRxiv, 2024
- Annals Oncol.Oncogenic extrachromosomal DNA identification using whole-genome sequencing from formalin-fixed glioblastomasAnnals of Oncology, 2024
- Neuro-OncologySTEM-07. CONSERVATION AND FAITHFUL REPRESENTATION OF CIRCULAR EXTRACHROMOSOMAL DNA IN ORTHOTOPIC PATIENT-DERIVED MEDULLOBLASTOMA XENOGRAFTSNeuro-Oncology, 2024
- bioRxivAmpliconSuite: an end-to-end workflow for analyzing focal amplifications in cancer genomesbioRxiv, 2024
- Neuro-OncologyMETB-08. CIRCULAR EXTRACHROMOSOMAL DNA IS ASSOCIATED WITH POOR SURVIVAL IN CHILDHOOD CANCER TYPESNeuro-Oncology, 2024
- JIDLB1067 Chromosomal structural variants but not extrachromosomal DNAs are common in Merkel cell carcinomaJournal of Investigative Dermatology, 2024
- Inhibition of novel human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancer2024
- Cancer Gen.13. AmpliconSuite: Analyzing focal amplifications in cancer genomesCancer Genetics, 2024
- Research SquareInhibition of novel human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancerResearch Square, 2024
- Nature GeneticsMapping extrachromosomal DNA amplifications during cancer progressionNature genetics, 2024
- ESMO Open111MO Extrachromosomal DNA drives oncogene spatial heterogeneity in IDH-wildtype glioblastomasESMO Open, 2024
- bioRxivExtrachromosomal DNA driven oncogene spatial heterogeneity and evolution in glioblastomabioRxiv, 2024
- NatureCoordinated inheritance of extrachromosomal DNAs in cancer cellsNature, 2024
- NatureEnhancing transcription–replication conflict targets ecDNA-positive cancersNature, 2024
- NatureOrigins and impact of extrachromosomal DNANature, 2024
- BloodA Single Mutation in the SENP1 Region Regulates the Excessive Erythropoiesis in the AndesBlood, 2024
- Cancer Sci.Contribution of human-viral hybrid ecDNA accumulation to the cancer life cycle and potential for novel targeted therapyIn CANCER SCIENCE, 2024
2023
- bioRxivBreakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome changebioRxiv, 2023
- bioRxivImmortalization and transformation of primary cells mediated by engineered ecDNAsbioRxiv, 2023
- Nature Comms.A deep population reference panel of tandem repeat variationNature Communications, 2023
- PNASIntegrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneityProceedings of the National Academy of Sciences, 2023
- NatureExtrachromosomal DNA in the cancerous transformation of Barrett’s oesophagusNature, 2023
- Bioinf. AdvancesTRviz: a Python library for decomposing and visualizing tandem repeat sequencesBioinformatics Advances, 2023
- bioRxivCoordinated inheritance of extrachromosomal DNA species in human cancer cellsbioRxiv, 2023
- NatureEpigenetic dysregulation from chromosomal transit in micronucleiNature, 2023
- Eur. J. Hum. Genet.Variable number tandem repeats (VNTRs) as modifiers of breast cancer risk in carriers of BRCA1 185delAGEuropean Journal of Human Genetics, 2023
- Nature GeneticsCircular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastomaNature genetics, 2023
- Environ. Intl.Multi-tissue proteogenomic analysis for mechanistic toxicology studies in non-model speciesEnvironment International, 2023
- DNA BarcodingAnalyses of nuclear reads obtained using genome skimmingIn DNA Barcoding: Methods and Protocols, 2023
2022
- ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge’s diseaseExperimental & molecular medicine, 2022
- Cancer Discov.Plasticity of extrachromosomal and intrachromosomal BRAF amplifications in overcoming targeted therapy dosage challengesCancer discovery, 2022
- Hum. Mol. GeneticsHeterozygous Tropomodulin 3 mice have improved lung vascularization after chronic hypoxiaHuman Molecular Genetics, 2022
- Ann. Rev. GHGExtrachromosomal DNA in cancerAnnual review of genomics and human genetics, 2022
- NAR GenomicsFastViFi: Fast and accurate detection of (Hybrid) Viral DNA and RNANAR genomics and bioinformatics, 2022
- Neuro-OncologyINTEGRATED ANALYSIS OF SINGLE CELL CHROMATIN ACCESSIBILITY AND RNA EXPRESSION IDENTIFIED COMMON VULNERABILITY DESPITE GLIOBLASTOMA HETEROGENEITYIn NEURO-ONCOLOGY, 2022
- Nature GeneticsThe evolutionary dynamics of extrachromosomal DNA in human cancersNature genetics, 2022
- Ann. Rev. PathExtrachromosomal DNA: an emerging hallmark in human cancerAnnual Review of Pathology: Mechanisms of Disease, 2022
- RECOMBUncertainty quantification using subsampling for assembly-free estimates of genomic distance and phylogenetic relationshipsIn International Conference on Research in Computational Molecular Biology, 2022
- NatureMapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNANature, 2022
- ACM-BCBDeepViFi: detecting oncoviral infections in cancer genomes using transformersIn Proceedings of the 13th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics, 2022
- Eur. J. Hum. Genet.Prevalence of hereditary tubulointerstitial kidney diseases in the German Chronic Kidney Disease studyEuropean Journal of Human Genetics, 2022
- iScienceDetecting tandem repeat variants in coding regions using code-adVNTRIscience, 2022
- iScienceOptical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19Iscience, 2022
- bioRxivExtrachromosomal DNA in the cancerous transformation of Barrett’s esophagusbioRxiv, 2022
- bioRxivEpigenetic dysregulation from chromosomal transit in micronucleiBioRxiv, 2022
- Nature GeneticsTargeted profiling of human extrachromosomal DNA by CRISPR-CATCHNature genetics, 2022
- Nature CancerForm follows function in cancer genomesNature Cancer, 2022
- Cell Syst.Quantifying the uncertainty of assembly-free genome-wide distance estimates and phylogenetic relationships using subsamplingCell systems, 2022
- Targeting nad biosynthesis in the treatment of cancerMay 2022US Patent App. 17/438,610
- Compositions and methods for modulating transcriptional activity of amplified oncogenes contained on extrachromosomal dnaJan 2022US Patent App. 17/311,980
- Methods of diagnosing and treating cancer targeting extrachromosomal dnaFeb 2022US Patent App. 17/518,396
- METHODS AND COMPOSITIONS FOR DETECTING ecDNANov 2022US Patent App. 17/746,748
2021
- PatternsFaNDOM: Fast nested distance-based seeding of optical mapsPatterns, 2021
- NAR GenomicsCONSULT: accurate contamination removal using locality-sensitive hashingNAR Genomics and Bioinformatics, 2021
- bioRxivComprehensive analysis of clustered mutations in cancer reveals recurrent APOBEC3 mutagenesis of ecDNAbioRxiv, 2021
- Nature Comms.Variable number tandem repeats mediate the expression of proximal genesNature communications, 2021
- ACM-BCBA CNN-based cell tracking method for multi-slice intravital imaging dataIn Proceedings of the 12th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics, 2021
- bioRxivPrinciples of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancersBioRxiv, 2021
- Neuro-OncologyOMIC-01. THE LANDSCAPE OF EXTRACHROMOSOMAL CIRCULAR DNA IN MEDULLOBLASTOMA SUBGROUPSNeuro-Oncology, 2021
- medRxivHost genome analysis of structural variations by optical genome mapping provides clinically valuable insights into genes implicated in critical immune, viral infection, and viral replication pathways in patients with severe COVID-19medRxiv, 2021
- NatureecDNA hubs drive cooperative intermolecular oncogene expressionNature, 2021
- Clin Cancer ResExtrachromosomal DNA in HPV-mediated oropharyngeal cancer drives diverse oncogene transcriptionClinical Cancer Research, 2021
- Nature Comms.Multiple mechanisms drive genomic adaptation to extreme O2 levels in Drosophila melanogasterNature communications, 2021
- Extrachromosomal DNA (ecDNA) in cancer pathogenesisCurrent opinion in genetics & development, 2021
- PLOS Comp. Bio.Estimating repeat spectra and genome length from low-coverage genome skims with RESPECTPLoS computational biology, 2021
- bioRxivThe landscape of extrachromosomal circular DNA in medulloblastomabioRxiv, 2021
- Methods of diagnosing and treating cancer targeting extrachromosomal DNADec 2021US Patent 11,193,164
2020
- Nature Comms.
- IJROBPLong-read RNA-Seq of human papillomavirus-associated head and neck cancer reveals novel alternatively spliced viral RNA isoformsInternational Journal of Radiation Oncology, Biology, Physics, 2020
- Beyond DNA barcoding: The unrealized potential of genome skim data in sample identification2020
- FASEBOxygen-Directed Laboratory Evolution and Conserved Mechanisms Underlying Hypoxia ToleranceThe FASEB Journal, 2020
- Nature GeneticsExtrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancersNature genetics, 2020
- bioRxivAmpliconReconstructor: Integrated analysis of NGS and optical mapping resolves the complex structures of focal amplifications in cancerbioRxiv, 2020
- Extrachromosomal DNA (ecDNA) carrying amplified oncogenes as a biomarker for insensitivity to pembrolizumab treatment in gastric cancer patients.2020
- FASEBIdentification of Candidate Genes Involved in the Survival of Drosophila in Extreme O2 EnvironmentsThe FASEB Journal, 2020
- The impact of contaminants on the accuracy of genome skimming and the effectiveness of exclusion read filtersMolecular Ecology Resources, 2020
- Nature Comms.AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplificationsNature communications, 2020
- Nature Comms.Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cellsNature communications, 2020
2019
- Cell SystComputing the statistical significance of overlap between genome annotations with iStatCell systems, 2019
- bioRxivA Note on Computing Interval Overlap StatisticsbioRxiv, 2019
- JPRProteogenomic annotation of Chinese hamsters reveals extensive novel translation events and endogenous retroviral elementsJournal of proteome research, 2019
- NatureNAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodellingNature, 2019
- Nature Rev. CancerExtrachromosomal oncogene amplification in tumour pathogenesis and evolutionNature Reviews Cancer, 2019
- NatureCircular ecDNA promotes accessible chromatin and high oncogene expressionNature, 2019
- Genome Bio.Skmer: assembly-free and alignment-free sample identification using genome skimsGenome biology, 2019
- bioRxivCancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor developmentbioRxiv, 2019
- Nature Comms.Exploring the landscape of focal amplifications in cancer using AmpliconArchitectNature communications, 2019
- bioRxivFrequent extrachromosomal oncogene amplification drives aggressive tumorsbioRxiv, 2019
- iScienceEcSeg: semantic segmentation of metaphase images containing extrachromosomal DNAIscience, 2019
- Eur. J. Hum. Genet.Novel insight into the genetic basis of high-altitude pulmonary hypertension in Kyrgyz highlandersEuropean Journal of Human Genetics, 2019
- bioRxivGlioblastomas derived from genetically modified pluripotent stem cells recapitulate pathobiologyBioRxiv, 2019
- Methods of treating extrachromosomal dna expressing cancers2019
2018
- Cell Syst.Proteostorm: An ultrafast metaproteomics database search frameworkCell systems, 2018
- Nature MethodsIdentifying the favored mutation in a positive selective sweepNature methods, 2018
- Nuc. Acids. ResViFi: accurate detection of viral integration and mRNA fusion reveals indiscriminate and unregulated transcription in proximal genomic regions in cervical cancerNucleic acids research, 2018
- bioRxivReconstructing and characterizing focal amplifications in cancer using AmpliconArchitectbioRxiv, 2018
- JPMHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collectionJournal of proteomics, 2018
- RECOMBTargeted Genotyping of Variable Number Tandem Repeats with AdVNTRIn Research in Computational Molecular Biology, 2018
- Genome Res.Targeted genotyping of variable number tandem repeats with adVNTRGenome research, 2018
- Whole-Genome-Sequencing Reveals Involvement of Mitochondria-Dependent Apoptotic Genes in High Altitude Pulmonary HypertensionIn B108. PULMONARY HYPERTENSION: THE LATEST FINDINGS, 2018
2017
- GeneticsCLEAR: Composition of likelihoods for evolve and resequence experimentsGenetics, 2017
- New insights into the genetic basis of Monge’s disease and adaptation to high-altitudeMolecular biology and evolution, 2017
- PNASUltraaccurate genome sequencing and haplotyping of single human cellsProceedings of the National Academy of Sciences, 2017
- JMMHigh-altitude adaptation in humans: from genomics to integrative physiologyJournal of Molecular Medicine, 2017
- bioRxivFine-mapping the favored mutation in a positive selective sweepbioRxiv, 2017
- Research in Computational Molecular Biology2017
- Genome Res.HapCUT2: robust and accurate haplotype assembly for diverse sequencing technologiesGenome research, 2017
- BloodMolecular basis of hypoxia-induced excessive erythrocytosis: critical role of SENP1 gene regulationBlood, 2017
- The antibody repertoire of colorectal cancerMolecular & Cellular Proteomics, 2017
- NatureExtrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneityNature, 2017
2016
- Appl. Environ. Microbiol.Diversity, productivity, and stability of an industrial microbial ecosystemApplied and environmental microbiology, 2016
- JEDSenp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge’s diseaseJournal of Experimental Medicine, 2016
- PLOS Genet.Correction: Predicting Carriers of Ongoing Selective Sweeps without Knowledge of the Favored AllelePLoS genetics, 2016
- Nuc. Acids. ResInPhaDel: integrative shotgun and proximity-ligation sequencing to phase deletions with single nucleotide polymorphismsNucleic acids research, 2016
- CellIntegrated proteogenomic characterization of human high-grade serous ovarian cancerCell, 2016
2015
- RECOMBHaplotype Allele Frequency (HAF) score: predicting carriers of ongoing selective sweeps without knowledge of the adaptive alleleIn International Conference on Research in Computational Molecular Biology, 2015
- JPRAdvanced proteogenomic analysis reveals multiple peptide mutations and complex immunoglobulin peptides in colon cancerJournal of proteome research, 2015
- Advanced Proteogenomic Analysis Reveals Multiple Peptide Mutations and Complex Immunoglobulin Peptides in Colon Cancer2015
- PLOS OneThe TGF\beta1 promoter SNP C-509T and food sensitization promote esophageal remodeling in pediatric eosinophilic esophagitisPloS one, 2015
- CirculationHeterozygous Endothelin Receptor Type B Knockout Confers Cardiac Resistance to Extreme Hypoxia in MiceCirculation, 2015
- PLOS Genet.Predicting carriers of ongoing selective sweeps without knowledge of the favored allelePLoS genetics, 2015
- PNASEndothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote miceProceedings of the National Academy of Sciences, 2015
- JCBReconstructing breakage fusion bridge architectures using noisy copy numbersJournal of Computational Biology, 2015
- Genet. Epidem.Genetic simulation tools for post-genome wide association studies of complex diseasesGenetic epidemiology, 2015
- ACS Infect. Dis.Next-generation sequencing of Plasmodium vivax patient samples shows evidence of direct evolution in drug-resistance genesACS infectious diseases, 2015
- Collaborative Research: ABI Innovation: Computational population-genetic analysis for detection of soft selective sweepsNSF Award Number 1458557. Directorate for Biological Sciences, 2015
2014
- BioinformaticsUsing Genome Query Language to uncover genetic variationBioinformatics, 2014
- JPRProteogenomic database construction driven from large scale RNA-seq dataJournal of proteome research, 2014
- BioinformaticsInferring gene ontologies from pairwise similarity dataBioinformatics, 2014
- Phys.The genetic basis of chronic mountain sicknessPhysiology, 2014
- An automated proteogenomic method uses mass spectrometry to reveal novel genes in Zea maysMolecular & Cellular Proteomics, 2014
- Annotation of the zebrafish genome through an integrated transcriptomic and proteomic analysisMolecular & cellular proteomics, 2014
- Nuc. Acids. ResThe elusive evidence for chromothripsisNucleic acids research, 2014
- Genome Res.Amplification and thrifty single-molecule sequencing of recurrent somatic structural variationsGenome Research, 2014
- Genome Bio.Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genesGenome biology, 2014
- ProteomicsProteogenomic strategies for identification of aberrant cancer peptides using large-scale next-generation sequencing dataProteomics, 2014
2013
- WABICerulean: a hybrid assembly using high throughput short and long readsIn International workshop on algorithms in bioinformatics, 2013
- Genome Bio.Virmid: accurate detection of somatic mutations with sample impurity inferenceGenome biology, 2013
- Using Genome Query Language (GQL) to uncover genetic variation2013
- BMC Bioinform.Evaluating genome architecture of a complex region via generalized bipartite matchingBMC bioinformatics, 2013
- PNASAn algorithmic approach for breakage-fusion-bridge detection in tumor genomesProceedings of the National Academy of Sciences, 2013
- GeneticsLearning natural selection from the site frequency spectrumGenetics, 2013
- Nuc. Acids. ResReprever: resolving low-copy duplicated sequences using template driven assemblyNucleic acids research, 2013
- CACMAbstractions for genomicsCommunications of the ACM, 2013
- Genome Bio.On the design of clone-based haplotypingGenome biology, 2013
- BioinformaticsWessim: a whole-exome sequencing simulator based on in silico exome captureBioinformatics, 2013
- arXivDetecting Breakage Fusion Bridge cycles in tumor genomes–an algorithmic approacharXiv preprint arXiv:1301.2610, 2013
- AJHGWhole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlandersThe American Journal of Human Genetics, 2013
2012
- Sci. Trans. MedExome sequencing can improve diagnosis and alter patient managementScience translational medicine, 2012
- JAMIAiDASH: integrating data for analysis, anonymization, and sharingJournal of the American Medical Informatics Association, 2012
- PLOS OneSample reproducibility of genetic association using different multimarker TDTs in genome-wide association studies: characterization and a new approachPLoS One, 2012
- RECOMBModeling the breakage-fusion-bridge mechanism: combinatorics and cancer genomicsIn Annual International Conference on Research in Computational Molecular Biology, 2012
- Nature GeneticsDe novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephalyNature genetics, 2012
- JCBAccurate mass spectrometry based protein quantification via shared peptidesJournal of Computational Biology, 2012
- JCBCombinatorics of the breakage-fusion-bridge mechanismJournal of Computational Biology, 2012
- Genome Res.Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancerGenome research, 2012
- BioinformaticsSpeeding up tandem mass spectral identification using indexesBioinformatics, 2012
- Sample Reproducibility of Genetic Association Using Different2012
2011
- ProteomicsResurrection of a clinical antibody: Template proteogenomic de novo proteomic sequencing and reverse engineering of an anti-lymphotoxin-αantibodyProteomics, 2011
- JCBCompressing genomic sequence fragments using SlimGeneJournal of Computational Biology, 2011
- BMC Bioinform.Strobe sequence design for haplotype assemblyBMC bioinformatics, 2011
- Research in Computational Molecular Biology: 15th Annual International Conference, RECOMB 2011, Vancouver, BC, Canada, March 28-31, 2011. Proceedings2011
- BioinformaticsSensitive gene fusion detection using ambiguously mapping RNA-Seq read pairsBioinformatics, 2011
- Metabolic Network Analysis Demystified. Ed. Vineet Bafna, S. Cenk Shinalp. LNCS Sublibrary: SL 8-Bioinformatics2011
- On the Approximability of Reachability-Preserving Network OrientationsInternet Mathematics, 2011
- PNASExperimental selection of hypoxia-tolerant Drosophila melanogasterProceedings of the National Academy of Sciences, 2011
- Front. Genet.Tests of selection in pooled case-control data: an empirical studyFrontiers in Genetics, 2011
- JPRPractical 4′-phosphopantetheine active site discovery from proteomic samplesJournal of proteome research, 2011
- JPRAMASS: algorithm for MSI analysis by semi-supervised segmentationJournal of proteome research, 2011
- Visualization of the MS-Align algorithm results for the protein spectrum matchesDepartment of Bioengineering and Bioinformatics of MV Lomonosov Moscow State University, 2011
- On the approximability of reachability-preserving network orientationsInternet Mathematics, 2011
- ACM-BCB2011 Index IEEE/ACM Transactions on Computational Biology and Bioinformatics Vol. 8IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2011
- JCBPreface: satellite workshop on comparative genomics, research in computational molecular biology (RECOMB-CG 2010) prefaceJournal of Computational Biology, 2011
- JPRAutomated querying and identification of novel peptides using MALDI mass spectrometric imagingJournal of proteome research, 2011
- AF: Small: Algorithms for Genetics: Epistatic Interactions, Haplotype Assembly, and Selection SignaturesNSF Award Number 1115206. Directorate for Computer and Information Science and Engineering, 2011
2010
- RECOMBCompressing genomic sequence fragments using SlimGeneIn Annual International Conference on Research in Computational Molecular Biology, 2010
- JCBOptimizing PCR assays for DNA-based cancer diagnosticsJournal of Computational Biology, 2010
- Research article Construction of a medicinal leech transcriptome database and its application to the identification of leech homologs of neural and innate immune genes2010
- JCBProtein-protein interaction network evaluation for identifying potential drug targetsJournal of Computational Biology, 2010
- Deconvolution and database search of complex tandem mass spectra of intact proteinsMolecular & Cellular Proteomics, 2010
- Expansion of the mycobacterial “PUPylome”Molecular bioSystems, 2010
- BMC GenomicsDesigning deep sequencing experiments: detecting structural variation and estimating transcript abundanceBMC genomics, 2010
- Genome Bio.Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite levelGenome biology, 2010
- Template proteogenomics: sequencing whole proteins using an imperfect databaseMolecular & Cellular Proteomics, 2010
- ACM-BCBTCLUST: A fast method for clustering genome-scale expression dataIEEE/ACM transactions on computational biology and bioinformatics, 2010
- BioinformaticsRAPID detection of gene–gene interactions in genome-wide association studiesBioinformatics, 2010
- JPProteogenomics to discover the full coding content of genomes: a computational perspectiveJournal of proteomics, 2010
- FASEBMapping of peptides and proteins in Leech (Hirudo medicinalis) by Mass Spectrometry ImagingThe FASEB Journal, 2010
- PLOS Comp. Bio.A covering method for detecting genetic associations between rare variants and common phenotypesPLoS computational biology, 2010
- BMC GenomicsConstruction of a medicinal leech transcriptome database and its application to the identification of leech homologs of neural and innate immune genesBMC genomics, 2010
- Genome Bio.Deciphering the genetic basis of common diseases by integrated functional annotation of common and rare variantsGenome Biology, 2010
2009
- Genome Res.Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encodingGenome research, 2009
- JCBFast and accurate alignment of multiple protein networksJournal of computational biology, 2009
- RECOMB
- CSE280 Class Projects (Suggested)2009
2008
- Genome Res.An MCMC algorithm for haplotype assembly from whole-genome sequence dataGenome research, 2008
- JPRPhosphorylation-specific MS/MS scoring for rapid and accurate phosphoproteome analysisJournal of proteome research, 2008
- WABIAn algorithm for orienting graphs based on cause-effect pairs and its applications to orienting protein networksIn International Workshop on Algorithms in Bioinformatics, 2008
- JPRAccurate annotation of peptide modifications through unrestrictive database searchJournal of proteome research, 2008
- PNASDiscovery and revision of Arabidopsis genes by proteogenomicsProceedings of the national academy of sciences, 2008
- JCBStructural alignment of pseudoknotted RNAJournal of Computational Biology, 2008
- PLOS Comp. Bio.Evaluation of paired-end sequencing strategies for detection of genome rearrangements in cancerPLoS computational biology, 2008
- Genome Res.Comparative proteogenomics: combining mass spectrometry and comparative genomics to analyze multiple genomesGenome research, 2008
- A multidimensional chromatography technology for in-depth phosphoproteome analysisMolecular & Cellular Proteomics, 2008
- RECOMBFast and accurate alignment of multiple protein networksIn Annual International Conference on Research in Computational Molecular Biology, 2008
- RECOMBQnet: A tool for querying biological networksRECOMB 2007 and JCB, 2008
- BioinformaticsHapCUT: an efficient and accurate algorithm for the haplotype assembly problemBioinformatics, 2008
- Evaluation of Paired-End Sequencing Strategies for Detection of Genome Rearrangements in2008
2007
- RECOMBQNet: a tool for querying protein interaction networksIn Annual International Conference on Research in Computational Molecular Biology, 2007
- Integrating scientific culturesMolecular Systems Biology, 2007
- JCBA decomposition theory for phylogenetic networks and incompatible charactersJournal of Computational Biology, 2007
- Genome Res.Whole proteome analysis of post-translational modifications: applications of mass-spectrometry for proteogenomic annotationGenome research, 2007
- Genome Res.Evidence for large inversion polymorphisms in the human genome from HapMap dataGenome research, 2007
- PLOS BioThe diploid genome sequence of an individual humanPLoS biology, 2007
- PLOS BioThe Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein familiesPLoS biology, 2007
- Genome Res.Improving gene annotation using peptide mass spectrometryGenome research, 2007
- Systems Biology and Computational Proteomics: Joint RECOMB 2006 Satellite Workshops on Systems Biology, and on Computational Proteomics, San Diego, CA, USA, December 1-3, 2006, Revised Selected Papers2007
- Integrating scientific culturesMolecular Systems Biology, 2007
- BioinformaticsOptimization of primer design for the detection of variable genomic lesions in cancerBioinformatics, 2007
- Phosphorylation-specific MS/MS scoringIn MOLECULAR & CELLULAR PROTEOMICS, 2007
- Systems biology and computational proteomicsLecture notes in computer science, 2007
2006
- Nature ProtocolsUnrestrictive identification of post-translational modifications through peptide mass spectrometryNature protocols, 2006
- CSBEXPLORING THE OCEAN’S MICROBES: SEQUENCING THE SEVEN SEASIn Computational Systems Bioinformatics, 2006
- RECOMBStructural alignment of pseudoknotted RNAIn Annual International Conference on Research in Computational Molecular Biology, 2006
- JCBInference about recombination from haplotype data: lower bounds and recombination hotspotsJournal of Computational Biology, 2006
- BioinformaticsA sequence-based filtering method for ncRNA identification and its application to searching for riboswitch elementsBioinformatics, 2006
- JPRAge-related changes in human crystallins determined from comparative analysis of post-translational modifications in young and aged lens: does deamidation contribute to crystallin insolubility?Journal of proteome research, 2006
- Identification of informative genetic markersMar 2006US Patent App. 11/040,652
- JCBConsensus folding of unaligned RNA sequences revisitedJournal of computational biology, 2006
2005
- RECOMBImproved recombination lower bounds for haplotype dataIn Annual International Conference on Research in Computational Molecular Biology, 2005
- Anal. Chem.InsPecT: identification of posttranslationally modified peptides from tandem mass spectraAnalytical chemistry, 2005
- RECOMBConsensus folding of unaligned RNA sequences revisitedIn Annual International Conference on Research in Computational Molecular Biology, 2005
- Theor. Comp. Sci.Polynomial and APX-hard cases of the individual haplotyping problemTheoretical Computer Science, 2005
- Identification of post-translational modifications via blind search of mass-spectraIn 2005 IEEE Computational Systems Bioinformatics Conference (CSB’05), 2005
- Genome Res.Orthologous repeats and mammalian phylogenetic inferenceGenome Research, 2005
- Nuc. Acids. Res.Orthologous repeats and mammalian phylogenetic inference. Genome ResIn Nucleic Acids Res, 2005
- ACM-BCBSearching genomes for noncoding RNA using FastRIEEE/ACM Transactions on Computational Biology and Bioinformatics, 2005
- JPRPeptide sequence tags for fast database search in mass-spectrometryJournal of proteome research, 2005
- ACM-BCB2005 Index IEEE/ACM Transactions on Computational Biology and Bioinformatics Vol. 2IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2005
- Novel Algorithms for NcRNA Discovery and RNA Structure PredictionNSF Award Number 0516440. Directorate for Biological Sciences, 2005
2004
- Mass spectrometry and computational proteomicsEncyclopedia of Genetics, Genomics, Proteomics and Bioinformatics, 2004
- Anal. Chem.Shotgun protein sequencing by tandem mass spectra assemblyAnalytical chemistry, 2004
- Pattern matching algorithms2004
- Genome Res.Optimal haplotype block-free selection of tagging SNPs for genome-wide association studiesGenome research, 2004
- ACM-BCBThe number of recombination events in a sample history: conflict graph and lower boundsIEEE/ACM Transactions on Computational Biology and Bioinformatics, 2004
- JCBA note on efficient computation of haplotypes via perfect phylogenyJournal of Computational Biology, 2004
- IEEE CSBFastR: Fast database search tool for non-coding RNAIn Proceedings. 2004 IEEE Computational Systems Bioinformatics Conference, 2004. CSB 2004., 2004
2003
- JCBHaplotyping as perfect phylogeny: A direct approachJournal of Computational Biology, 2003
- RECOMBOn de novo interpretation of tandem mass spectra for peptide identificationIn Proceedings of the seventh annual international conference on Research in computational molecular biology, 2003
- DMTCSCombinatorial problems arising in SNP and haplotype analysisIn International Conference on Discrete Mathematics and Theoretical Computer Science, 2003
- ScienceThe dog genome: survey sequencing and comparative analysisScience, 2003
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